I have a hypothesis about bloating memory: it will stop mattering soon. Solid-state non-volatile storage at RAM speeds on a fast bus will allow for terabytes of memory -- and increase with the unimpeded Moore's Law of storage. I know of at least one company, FusionIO, offering this as a product already.
If you can store all but the largest databases in memory, why not use a web framework that doesn't bother with a "real" DB like MySQL? But clearly, I'm talking about memory hungry systems generally, and not memory leaks.
